With its numerous mountain watercourses and the abundance of fish, as well as the large number of manmade lakes, the Bregalnica region has excellent conditions for fishing tourism. The best conditions for this are on Lake Kalimanci, Gratce Lake, Berovo Lake, Sandanski Lake (this is its main purpose), Losana Lake near the village of Trabotiviste, Pisicko Lake, then Bregalnica from Kalimanci to the entrance into Kocansko Pole, Zletkovska River to the village of Zletovo, Osojnica River through the gorge, etc.
According to the fishing plans for the Bregalnica basin (2011), the Bregalnica area is divided into 5 fishing districts from the source (Bregalnica 1) to the mouth in Svetnikolska River (Bregalnica 5). In the rivers’ upper reaches there is river trout, while in the lower sections there is common nase, chub, gudgeon, carp, barbel, etc. In Kalimanci Lake there is catfish as well.
Unfortunately, the pollution of Bregalnica River with inorganic and organic pollutants affects the fish. By protecting the water areas fish and water biodiversity are also protected, which is also an opportunity for development of fishing tourism.